gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize the tumor-associated peptide–MHC II complex via their TCRs and directly kill target cells through perforin/granzyme-mediated cytolysis (with possible Fas–FasL and cytokine-mediated effects).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognized by CD4+ TILs; shared TAA epitopes presented by pMHC-II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06342336
disease_id_num_tar_ref
65
drug_id_num_tar_ref
157