gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine induces HPV16 E6/E7–specific CD8+ T cells that recognize E6 peptides on MHC I and kill tumor cells via CTL mechanisms (perforin/granzyme, Fas–FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
HPV16 oncoprotein antigen presented on MHC I/II on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06589609
disease_id_num_tar_ref
606
drug_id_num_tar_ref
1698