gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Elranatamab links CD3 on T cells to BCMA on target cells, forming an immune synapse and triggering T-cell degranulation (perforin/granzymes) to kill BCMA+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface TNF receptor superfamily member; overexpressed on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06479954
disease_id_num_tar_ref
631
drug_id_num_tar_ref
1766