gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Glofitamab bridges CD20 on B cells to CD3 on T cells, activating T cells to form an immune synapse and kill CD20+ cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
bivalent binding in 2:1 CD20×CD3 format
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06481826
disease_id_num_tar_ref
646
drug_id_num_tar_ref
1803