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gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind BCMA on target cells and induce cytotoxic T-cell killing via perforin/granzyme-mediated lysis and apoptosis (and Fas–FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
nct_id_tar_ref
NCT06553898
disease_id_num_tar_ref
78
drug_id_num_tar_ref
197