gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-DLL3 CAR T cells bind DLL3 on target cells, activate, and kill via perforin/granzyme-mediated cytotoxicity leading to apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated cell-surface Notch pathway ligand overexpressed in SCLC/LCNEC
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06384482
disease_id_num_tar_ref
660
drug_id_num_tar_ref
1846