gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 antibody binds CD20 on B cells, recruiting effector mechanisms to kill them: Fc-mediated ADCC by NK cells, complement activation (CDC) forming MAC, antibody-dependent phagocytosis by macrophages, and apoptosis upon crosslinking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06412068
disease_id_num_tar_ref
666
drug_id_num_tar_ref
1861