gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA engagement activates the dual CAR T cells to form an immune synapse and kill BCMA+ cells via perforin/granzyme-mediated cytolysis (and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06733610
disease_id_num_tar_ref
667
drug_id_num_tar_ref
1867