gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The BCMA×CD3 bispecific bridges T cells to BCMA+ cells, activating TCR/CD3 and inducing perforin/granzyme-mediated cytolysis and cytokine-driven killing of the BCMA-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06574568
disease_id_num_tar_ref
671
drug_id_num_tar_ref
1885