gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Viral-vector vaccine transduces APCs to present HPV E6 peptides on MHC I/II, inducing Th1-biased HPV-specific CD8+ T cells that recognize E6 peptide–MHC on tumor cells and kill them via perforin/granzyme-mediated cytolysis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Presented via MHC I/II; ETSD-enhanced antigen processing
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05976828
disease_id_num_tar_ref
684
drug_id_num_tar_ref
1909