gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-specific CAR T cells bind CD19 on target cells and, upon CAR activation, directly kill them via perforin/granzyme-mediated cytolysis and Fas–FasL apoptotic signaling.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface B-cell lineage antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06387121
disease_id_num_tar_ref
693
drug_id_num_tar_ref
1939