gene_symbol
CLDN6
hgnc_id
HGNC:2048
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CTIM-76 bridges CD3 on T cells to CLDN6 on tumor cells, forming an immune synapse and activating T cells to kill CLDN6+ cells via perforin/granzyme-mediated cytolysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06515613
disease_id_num_tar_ref
730
drug_id_num_tar_ref
2030