gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CTIM-76 binds CD3E on T cells to recruit and activate them; the activated T cells kill CLDN6-positive tumor cells via perforin/granzyme–mediated cytolysis, not the CD3-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor/CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06515613
disease_id_num_tar_ref
730
drug_id_num_tar_ref
2030