gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind the B-cell antigen, become activated, and kill the antigen-expressing cells via contact-dependent cytotoxicity (perforin/granzyme-mediated apoptosis and Fas–FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Trial indicates CAR-T is B-cell directed but does not specify the antigen (e.g., CD19/CD20/CD22 not stated).
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT07059741
disease_id_num_tar_ref
749
drug_id_num_tar_ref
2082