gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and triggers Fc-mediated ADCC (enhanced by low-fucose Fc) and complement-dependent cytotoxicity, leading to lysis/apoptosis of CD20+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05152459
disease_id_num_tar_ref
759
drug_id_num_tar_ref
2115