gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine-transduced APCs present E7 peptides to prime HPV16 E7–specific CD8+ T cells; these CTLs recognize E7-derived peptides on MHC I of HPV-positive cells and kill them via perforin/granzyme-mediated cytolysis (and Fas–FasL apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
viral antigen (HPV type 16)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06319963
disease_id_num_tar_ref
788
drug_id_num_tar_ref
2195