gene_symbol
TACSTD2
hgnc_id
HGNC:11530
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-NK cells bind TROP2 on target cells, triggering NK activation and degranulation with perforin/granzyme-mediated lysis/apoptosis (with contributory cytokine effects).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Surface glycoprotein overexpressed on many solid tumors
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06066424
disease_id_num_tar_ref
791
drug_id_num_tar_ref
2199