gene_symbol
AFP
hgnc_id
HGNC:317
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs use native TCRs to recognize AFP-derived peptides presented on MHC (primarily class I) on tumor cells, then kill them via cytotoxic T-cell effector mechanisms (perforin/granzyme and Fas–FasL), with supportive cytokines.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented by HLA class I and/or II on HCC cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06463522
disease_id_num_tar_ref
94
drug_id_num_tar_ref
243