gene_symbol
CD33
hgnc_id
HGNC:1659
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD33 CAR T cells bind CD33 and induce T-cell–mediated killing via perforin/granzyme release and death-receptor signaling.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface myeloid antigen (SIGLEC3)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05945849
disease_id_num_tar_ref
840
drug_id_num_tar_ref
2317