gene_symbol
MAGEA1
hgnc_id
HGNC:6796
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Patient-derived TILs recognize MAGE-A1 peptide epitopes presented on MHC via their native TCRs and kill target cells through perforin/granzyme-mediated cytolysis (and Fas–FasL/cytokine-mediated apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Cancer-testis antigen; presented by HLA class I/II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06463522
disease_id_num_tar_ref
94
drug_id_num_tar_ref
243