gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-GPRC5D CAR T cells bind GPRC5D on target cells and, upon CAR activation, kill them via T-cell cytolysis (perforin/granzyme and Fas–FasL–mediated apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06271252
disease_id_num_tar_ref
867
drug_id_num_tar_ref
2381