gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rituximab binds CD20 on B cells and depletes them via Fc-mediated ADCC by NK/macrophages, complement-dependent cytotoxicity, and induction of apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; expressed from pre-B to mature B cells, not plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05758831
disease_id_num_tar_ref
888
drug_id_num_tar_ref
2424