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gene_symbol
TERT
hgnc_id
HGNC:11730
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused TILs recognize TERT peptide–MHC complexes via native TCRs and kill target cells through perforin/granzyme-mediated cytolysis (and Fas–FasL apoptosis), with supportive cytokine effects.
enzyme_product
On
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented by HLA class I/II
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06463522
disease_id_num_tar_ref
94
drug_id_num_tar_ref
243