gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine primes CMV pp65–specific CD8+ T cells that recognize pp65 peptides on MHC I of expressing cells and kill them via perforin/granzyme (and Fas–FasL) pathways; the drug itself does not directly kill cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
26-aa synthetic long peptide derived from HCMV UL83/pp65, formulated in Montanide ISA 51 for broad MHC I/II presentation
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05096481
disease_id_num_tar_ref
894
drug_id_num_tar_ref
2437