gene_symbol
EPCAM
hgnc_id
HGNC:11529
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-EpCAM mAb binds EpCAM on tumor cells and engages immune effectors via its Fc to mediate ADCC and complement activation (CDC), leading to lysis of EpCAM-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated antigen (TAA)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05687682
disease_id_num_tar_ref
916
drug_id_num_tar_ref
2495