gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-T cells bind CD19 on target cells, activate, and kill via T-cell cytotoxic mechanisms (perforin/granzyme-mediated apoptosis and Fas–FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface B-cell antigen; HLA-independent CAR binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06218602
disease_id_num_tar_ref
95
drug_id_num_tar_ref
244