gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD38 IgG1 binds CD38 on target cells and eliminates them via complement-dependent cytotoxicity, Fc-mediated ADCC by NK/effector cells, antibody-dependent phagocytosis, and apoptosis upon cross-linking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Transmembrane ectoenzyme (NADase/ADP-ribosyl cyclase)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05974969
disease_id_num_tar_ref
924
drug_id_num_tar_ref
2524