gene_symbol
TNFRSF13C
hgnc_id
HGNC:17755
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BAFFR-specific CAR T cells bind BAFFR on target B cells and, upon engagement, activate cytotoxic pathways (perforin/granzyme-mediated killing and death receptor signaling) to induce apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CD268; cell-surface TNF receptor on B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06191887
disease_id_num_tar_ref
934
drug_id_num_tar_ref
2547