gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-NK cells bind CD19 on target cells, become activated, and kill via degranulation with perforin/granzymes leading to lysis/apoptosis of CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR NK recognition of CD19 on B-lineage cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06557265
disease_id_num_tar_ref
937
drug_id_num_tar_ref
2558