gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Therapeutic arenavirus vaccine primes/expands HPV16 E6/E7–specific CD8+ T cells, which recognize E6-derived peptides on MHC I of HPV16+ cells and kill them via CTL mechanisms (perforin/granzyme, Fas–FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Viral antigen presented as peptide–MHC class I complexes on HPV16-positive tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06513884
disease_id_num_tar_ref
948
drug_id_num_tar_ref
2589