gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-directed CAR T cells bind CD19 on target cells and kill them via T cell cytotoxicity (immune synapse formation, perforin/granzyme release, and apoptosis pathways such as Fas-FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
dual CAR co-targeted with BCMA
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06497361
disease_id_num_tar_ref
960
drug_id_num_tar_ref
2633