gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize the patient-specific neoantigen peptide presented on MHC via their native TCRs and directly kill the tumor cell through perforin/granzyme release (with possible Fas–FasL and cytokine-mediated effects).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented by HLA class I and/or II on tumor cells; repertoire is patient-specific
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06191900
disease_id_num_tar_ref
961
drug_id_num_tar_ref
2634