gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize HPV E7 peptide presented on MHC via native TCRs and directly kill tumor cells through perforin/granzyme-mediated cytolysis (with possible Fas–FasL and cytokine effects).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Viral epitope from HPV16/18 E7 presented by HLA on HPV-positive cervical tumors
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06191900
disease_id_num_tar_ref
961
drug_id_num_tar_ref
2634