gene_symbol
CD7
hgnc_id
HGNC:1695
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD7 CAR T cells bind CD7 on target cells, become activated, and kill via perforin/granzyme-mediated cytolysis and apoptosis (with possible Fas/FasL and cytokine-mediated effects).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface glycoprotein on T cells and some NK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06316427
disease_id_num_tar_ref
7
drug_id_num_tar_ref
13