gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR engagement of CD19 on target cells activates the NK cell, causing degranulation with perforin and granzymes that induce lysis/apoptosis of CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-cell antigen; HLA-independent CAR recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06464861
disease_id_num_tar_ref
985
drug_id_num_tar_ref
2700