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gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-specific CAR engagement activates the engineered T cells to kill CD19+ cells via perforin/granzyme-mediated cytolysis and death-receptor pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen targeted by CAR
trial_id_tar_ref
nct_id_tar_ref
NCT06464861
disease_id_num_tar_ref
985
drug_id_num_tar_ref
2701