gene_symbol
IL7R
hgnc_id
HGNC:6024
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The CAR-T cells target and kill CD19+ B cells via CAR-mediated cytotoxicity. IL-7 secretion engages IL7R (CD127) on T cells to enhance their survival/proliferation; IL7R-expressing cells are not targeted or killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Receptor for secreted IL-7; supports T-cell survival/proliferation
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06464861
disease_id_num_tar_ref
985
drug_id_num_tar_ref
2701