gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19 CAR T cells bind CD19 on B-lineage cells; CAR signaling triggers perforin/granzyme release and death-receptor pathways (e.g., Fas/FasL), causing apoptosis/lysis of the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HLA-independent cell-surface B-cell marker
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06428188
disease_id_num_tar_ref
993
drug_id_num_tar_ref
2719