gene_symbol
ULBP3
hgnc_id
HGNC:14895
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR-NK cells bind ULBP3 on target cells, signal via DAP10/CD3ΞΆ, and kill through NK degranulation (perforin/granzyme-mediated cytolysis; may also engage death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand (stress-inducible)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05734898
disease_id_num_tar_ref
994
drug_id_num_tar_ref
2722