gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The anti-CD20 IgG1 binds CD20 on B cells and recruits immune effector mechanisms, causing antibody-dependent cellular cytotoxicity via FcγR-bearing cells, complement-dependent cytotoxicity via C1q activation, and apoptosis upon crosslinking
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-lymphocyte surface antigen; extracellular loop epitope
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05999604
disease_id_num_tar_ref
1080
drug_id_num_tar_ref
2938