gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine primes and expands neoantigen-specific CD8+ T cells, which recognize MHC I–presented neoantigen epitopes on tumor cells and kill them via perforin/granzyme and Fas–FasL pathways.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented by HLA-A/B/C on APCs; primes CD8+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06344156
disease_id_num_tar_ref
116
drug_id_num_tar_ref
310