Rabbit-derived polyclonal IgG targeting human T-cell antigens; depletes T cells (and some B/NK cells) via complement-dependent cytotoxicity, ADCC, and apoptosis.
Rabbit-derived polyclonal IgG that binds multiple human T‑cell antigens and depletes T cells (with some B/NK cell effects) via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and induction of apoptosis, producing profound lymphodepletion.
rATG includes antibodies against CD11a; binding to CD11a+ cells triggers complement-dependent cytotoxicity and Fc-mediated ADCC, with additional apoptosis, leading to depletion of those cells.
Rabbit-derived polyclonal IgG targeting human T-cell antigens; depletes T cells (and some B/NK cells) via complement-dependent cytotoxicity, ADCC, and apoptosis.
Rabbit-derived polyclonal IgG that binds multiple human T‑cell antigens and depletes T cells (with some B/NK cell effects) via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and induction of apoptosis, producing profound lymphodepletion.
Polyclonal IgG in rATG binds CD18 on leukocytes and triggers complement-dependent lysis and Fc-mediated ADCC/phagocytosis, with additional apoptosis induction, leading to direct depletion of CD18+ cells.
Rabbit-derived polyclonal IgG targeting human T-cell antigens; depletes T cells (and some B/NK cells) via complement-dependent cytotoxicity, ADCC, and apoptosis.
Rabbit-derived polyclonal IgG that binds multiple human T‑cell antigens and depletes T cells (with some B/NK cell effects) via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and induction of apoptosis, producing profound lymphodepletion.
rATG contains antibodies that bind CD28 on T cells, leading to complement-dependent lysis and Fc-mediated ADCC; cross-linking can also induce apoptosis.
Anti‑CD20 monoclonal antibody that mediates B‑cell depletion via ADCC, complement activation, and apoptosis.
Chimeric anti‑CD20 monoclonal antibody that binds CD20 on B cells and depletes CD20‑positive cells via antibody‑dependent cellular cytotoxicity (ADCC), complement‑dependent cytotoxicity (CDC), and induction of apoptosis.
Binds CD20 on B cells and kills via Fc-mediated ADCC, complement-dependent cytotoxicity (CDC), and direct induction of apoptosis.
Rabbit-derived polyclonal IgG targeting human T-cell antigens; depletes T cells (and some B/NK cells) via complement-dependent cytotoxicity, ADCC, and apoptosis.
Rabbit-derived polyclonal IgG that binds multiple human T‑cell antigens and depletes T cells (with some B/NK cell effects) via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and induction of apoptosis, producing profound lymphodepletion.
rATG contains antibodies that bind CD45 on leukocytes, triggering complement-dependent cytotoxicity and Fc-mediated ADCC/phagocytosis, and can induce apoptosis, leading to direct depletion of CD45+ cells.