gene_symbol
MET
hgnc_id
HGNC:7029
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific ADC binds c-MET on tumor cells, is internalized, and releases a cytotoxic payload in lysosomes that kills the target-expressing cell (with concurrent MET/EGFR signaling inhibition).
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Receptor tyrosine kinase
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06515990
disease_id_num_tar_ref
1217
drug_id_num_tar_ref
3310