gene_symbol
TBXT
hgnc_id
HGNC:11515
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The Ad5 vaccine transduces APCs to present brachyury peptides, priming brachyury-specific CD8+ T cells that recognize peptide–MHC I on tumor cells and kill them via perforin/granzyme (and Fas/FasL) cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor-associated antigen; intracellular transcription factor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06149481
disease_id_num_tar_ref
1358
drug_id_num_tar_ref
3672