gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The mRNA vaccine primes HPV-16–specific CD8+ T cells that recognize HPV-16 peptides on MHC I of infected/tumor cells and kill them via perforin/granzyme-mediated cytolysis (with CD4+ T-cell help).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Antigens encoded by the vaccine mRNA; processed and presented on MHC I/II to elicit HPV-16–specific T-cell responses
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06741150
disease_id_num_tar_ref
1436
drug_id_num_tar_ref
3884