gene_symbol
CD2
hgnc_id
HGNC:1639
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD2 on T cells and depletes them via complement-dependent lysis and Fc-mediated ADCC, with additional apoptosis induction upon crosslinking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06646497
disease_id_num_tar_ref
1451
drug_id_num_tar_ref
3924