gene_symbol
CD3D
hgnc_id
HGNC:1673
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD3 (including the CD3δ chain) on T cells and induces killing via complement-dependent cytotoxicity and Fc-mediated ADCC, and can also trigger apoptosis of the bound T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 complex component (TCR co-receptor)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06646497
disease_id_num_tar_ref
1451
drug_id_num_tar_ref
3924