gene_symbol
CD8A
hgnc_id
HGNC:1706
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD8α on T cells; Fc engagement triggers complement-dependent cytotoxicity and ADCC, and can induce apoptosis, depleting CD8+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cytotoxic T-cell co-receptor subunit
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06646497
disease_id_num_tar_ref
1451
drug_id_num_tar_ref
3924