gene_symbol
HLA-DRB1
hgnc_id
HGNC:4948
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal antibodies in ATG bind HLA-DR on target cells, triggering complement-dependent lysis and Fc-mediated ADCC/phagocytosis, leading to apoptosis/lysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class II beta chain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06646497
disease_id_num_tar_ref
1451
drug_id_num_tar_ref
3924