gene_symbol
LILRA4
hgnc_id
HGNC:15503
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Antibody-bound ILT7+ plasmacytoid dendritic cells are killed via enhanced FcγRIIIa-mediated ADCC, primarily by NK cells (perforin/granzyme-mediated lysis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Expressed on plasmacytoid dendritic cells; binding drives pDC depletion
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05540665
disease_id_num_tar_ref
1460
drug_id_num_tar_ref
3946